Leucose bij katten in Vlaanderen: Een brede kijk op de cijfers

Tine
Raes

Leucose bij katten in Vlaanderen: een brede kijk op de cijfers.

Hoe vaak komt leucose voor bij katten in Vlaanderen? Om hier antwoord op te krijgen werden Vlaamse organisaties bevraagd die katten opvangen (asielen en zwerfkattenorganisaties). Enkele van deze organisaties deelden hun testresultaten van leucosetesten. Van de 866 verzamelde testresultaten uit 2025 bleken 9 katten positief. Dit komt neer op een prevalentie van 1%.

Dit relatief lage prevalentiecijfer komt overeen met eerdere cijfers uit Europa en België, maar er waren te weinig en onvoldoende verspreide resultaten om een uitspraak te doen over de prevalentie in heel Vlaanderen. Wel brachten de resultaten enkele belangrijke inzichten over testen, preventieve maatregelen en dierenwelzijn. 

Wat is leucose? 

Sociaal contact speelt een belangrijke rol in overdracht.

Leucose is een infectieziekte veroorzaakt door een virus (het Feline leukemievirus). Het virus wordt voornamelijk overgedragen via speeksel of bloed van een geïnfecteerde kat. Daarom speelt (sociaal) contact tussen katten een belangrijke rol bij de overdracht (bv. het delen van eet- en drinkplekken, elkaar wassen, via bijtwonden, …). Ook kan een kattin het virus doorgeven aan haar kittens via de baarmoeder of moedermelk. 

Na blootstelling aan het virus kunnen er ernstige symptomen ontstaan zoals tumoren, bloedarmoede en een verzwakt immuunsysteem. Maar katten ontwikkelen niet altijd (meteen) symptomen. Er zijn verschillende infectie-uitkomsten en de prognose is sterk afhankelijk van de immuniteit, leeftijd, het subtype van het virus, de infectiedruk en genetische factoren. 

In sommige regio’s is leucose een grote oorzaak van sterfte bij katten. Eerdere studies hebben aangetoond dat de prevalentie in Europa relatief laag is. Er waren echter geen specifieke cijfers voor Vlaanderen, terwijl die wel van belang kunnen zijn voor correcte diagnose en het toepassen van preventieve maatregelen. 

Uit bevragingen bij organisaties in Vlaanderen kwam een prevalentie van 1%. De resultaten waren onvoldoende om een uitspraak te doen over de prevalentie in heel Vlaanderen. Toch bieden ze al waardevolle informatie. 


De prevalentie beïnvloedt de diagnose 

De betrouwbaarheid van een testresultaat hangt samen met de prevalentie van de ziekte.

Er kunnen enkele weken zitten tussen een besmetting en een positieve test. In combinatie met de verschillende infectie-uitkomsten zorgt het ervoor dat het in sommige gevallen nodig is om katten meerdere keren te testen (via een andere testmethode). Daarnaast heeft de prevalentie ook een invloed op de betrouwbaarheid van die testresultaten. Theoretisch gezien is er bij een lage prevalentie namelijk meer kans op vals positieve resultaten. Bij een prevalentie van 1% is bij de meest gebruikte testmethode van leucose (een immunochromatografietest) de kans dat een positief testresultaat vals positief is 66% tot 91%. Ondanks het beperkt aantal testresultaten kwam dit ook naar voren in de cijfers van de organisaties. 4 van de 9 positieve katten uit de testresultaten werden een tweede keer getest met een andere testmethode. Bij 3 van deze 4 katten kon op basis van de tweede test geconcludeerd worden dat het eerste testresultaat vals positief was. Deze 3 resultaten zijn opnieuw te weinig om een algemene conclusie te vormen, maar ze maken wel duidelijk waarom het in sommige gevallen nodig is om een positief testresultaat te herhalen. 

Deze informatie is belangrijk in het kader van dierenwelzijn. Er bestaat geen behandeling die leucose kan genezen, maar met de juiste opvolging kunnen katten met symptomen wel nog meerdere mooie jaren hebben. Voor zwerfkatten die niet herplaatst kunnen worden, ligt dit anders. Wanneer katten met een positieve test standaard worden geëuthanaseerd, bestaat het risico dat een kat met een vals positief resultaat onterecht wordt geëuthanaseerd. Anderzijds kan het ook nadelig zijn voor het welzijn van zwerfkatten om ze langdurig binnen of apart te houden in afwachting van een tweede test. Daarom is het belangrijk om bij een lage prevalentie rekening te houden met de betrouwbaarheid van de test en per situatie te bekijken wat de meest diervriendelijke beslissing is.  

Vaccinatie als preventieve maatregel

Vaccinatie is niet nodig of nuttig als standaard maatregel voor alle katten.

Vaccinatie voorkomt niet elke infectie-uitkomst, maar kan wel helpen om het ontstaan van ziekteverschijnselen te voorkomen. Toch is het niet nodig of nuttig om alle katten standaard te vaccineren tegen leucose. Zo zijn er bijvoorbeeld katten die geen risico lopen op besmetting en daarom niet gevaccineerd moeten worden. Ook bij katten die positief zijn, heeft vaccinatie geen nut meer.  

Er zijn richtlijnen die aanbevelen om katten altijd eerst te testen op leucose alvorens ze ertegen te vaccineren. Indien een kat al besmet is, maar nog niet positief test, kan vaccinatie zorgen voor een vals gevoel van bescherming. Of er kan in dat geval misschien ten onrechte geconcludeerd worden dat een vaccin niet heeft gewerkt wanneer de kat later toch symptomen ontwikkelt.

Dit betekent niet dat vaccinatie geen nut heeft. Zeker voor katten die een hoog risico lopen op besmetting, is het vaccin heel zinvol. Maar het is belangrijk om dit per kat en per situatie te beoordelen. 

In Vlaanderen was het vroeger verplicht om elke kat standaard te vaccineren tegen leucose bij het verhandelen. Sinds 13 maart 2026 is dit niet meer verplicht voor asielen, wat dus een terechte beslissing was.

Castratie als preventieve maatregel

Nog een andere belangrijke preventieve maatregel is castratie. Castratie zorgt over het algemeen voor minder agressie tussen katten, minder sociale interactie, minder territoriaal gedrag en minder paargedrag. Katers hebben hierdoor ook een kleinere home range. Bovendien kunnen kattinnen het virus dan niet meer overbrengen naar hun kittens. Hierdoor is er dus minder kans op overdracht van het virus. 

Er zijn organisaties die aanraden om bij beperkte middelen en een lage prevalentie eerder in te zetten op castratie op grote schaal en goede zorgen voor zwerfkatten dan standaard elke kat te testen en vaccineren.

Conclusie 

Er zijn nog meer verspreide testresultaten nodig om een exact beeld te krijgen van de prevalentie van leucose in Vlaanderen. Wat wel duidelijk is, is dat kennis over de prevalentie belangrijk is om testresultaten correct te interpreteren, preventieve maatregelen gericht toe te passen en beslissingen te nemen met het welzijn van katten als belangrijk uitgangspunt.

Bibliografie

Alcover, M. M., Basurco, A., Fernandez, A., Riera, C., Fisa, R., Gonzalez, A.,…Yzuel, A. (2021). A cross-sectional study of Leishmania infantum infection in stray cats in the city of Zaragoza (Spain) using serology and PCR. Parasites & vectors, 14(1), 178. 

Arjona, A., Escolar, E., Soto, I., Barquero, N., Martin, D., & Gomez-Lucia, E. (2000). Seroepidemiological survey of infection by feline leukemia virus and immunodeficiency virus in Madrid and correlation with some clinical aspects. Journal of Clinical Microbiology, 38(9), 3448-3449. 

Bandecchi, P., Dell’Omodarme, M., Magi, M., Palamidessi, A., & Prati, M. C. (2006). Feline leukaemia virus (FeLV) and feline immunodeficiency virus infections in cats in the Pisa district of Tuscany, and attempts to control FeLV infection in a colony of domestic cats by vaccination. Veterinary Record, 158(16), 555-557. 

Barrios, F., Suárez, G., Udell, M. A. R., & Damián, J. P. (2023). Characterization of the domestic cat population of Uruguay: breeds, coat colors, hair length, lifestyle, sex and spay/neuter status according to guardian report. Animals, 13(12), 1963. 

Besluit van de Vlaamse Regering. (2024, 24 mei). Besluit van van de Vlaamse Regering over de identificatie, registratie en sterilisatie van katten. Belgisch Staatsblad

Biezus, G., Machado, G., Ferian, P. E., da Costa, U. M., da Silva Pereira, L. H. H., Withoeft, J. A.,…Casagrande, R. A. (2019). Prevalence of and factors associated with feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) in cats of the state of Santa Catarina, Brazil. Comparative immunology, microbiology and infectious diseases, 63, 17-21. 

Bollez, A., De Rooster, H., Furcas, A., & Vandenabeele, S. (2018). Prevalence of external ear disorders in Belgian stray cats. Journal of feline medicine and surgery, 20(2), 149-154. 

Brown, R. (2007). FeLV and FIV in a cat population. The Veterinary Record, 161(11), 396. 

Burling, A. N., Levy, J. K., Scott, H. M., Crandall, M. M., Tucker, S. J., Wood, E. G., & Foster, J. D. (2017). Seroprevalences of feline leukemia virus and feline immunodeficiency virus infection in cats in the United States and Canada and risk factors for seropositivity. Journal of the American Veterinary Medical Association, 251(2), 187-194. 

Cafazzo, S., Bonanni, R., & Natoli, E. (2019). Neutering effects on social behaviour of urban unowned free-roaming domestic cats. Animals, 9(12), 1105. 

Calver, M. C., Crawford, H. M., & Fleming, P. A. (2020). Response to Wolf et al.: Furthering debate over the suitability of trap-neuter-return for stray cat management. Animals, 10(2), 362. 

Cano-Ortiz, L., Tochetto, C., Roehe, P. M., Franco, A. C., & Junqueira, D. M. (2022). Could phylogenetic analysis be used for feline leukemia virus (FeLV) classification? Viruses, 14(2), 249. 

Capa, M. J. C., Sarabia, M. P. V., Alcívar, J. A. E., Cedeño, I. T., & Valenzuela, F. L. J. (2025). Detection of Feline Leukemia virus p27 antigen by microELISA vs immunochromatographic tests in cats from Guayaquil. Centrosur Agraria, 1(24), 42-52. 

Carminato, A., Vascellari, M., Marchioro, W., Melchiotti, E., & Mutinelli, F. (2011). Microchip‐associated fibrosarcoma in a cat. Veterinary dermatology, 22(6), 565-569. 

Chen, R., Li, T. M., Merrick, H., Parrish, R. F., Bruno, V., Kwong, A.,…Litman, D. J. (1987). An internal clock reaction used in a one-step enzyme immunochromatographic assay of theophylline in whole blood. Clinical Chemistry, 33(9), 1521-1525. https://doi.org/10.1093/clinchem/33.9.1521

Chhetri, B. K., Berke, O., Pearl, D. L., & Bienzle, D. (2013). Comparison of the geographical distribution of feline immunodeficiency virus and feline leukemia virus infections in the United States of America (2000–2011). BMC veterinary research, 9(1), 2. 

Chiu, E. S., Hoover, E. A., & VandeWoude, S. (2018). A retrospective examination of feline leukemia subgroup characterization: viral interference assays to deep sequencing. Viruses, 10(1), 29. 

Chiu, E. S., McDonald, C. A., Gagne, R. B., Dunkleberger, H., Moxcey, M., & VandeWoude, S. (2024). Endogenous feline leukemia virus long terminal repeat integration site diversity is highly variable in related and unrelated domestic cats. Retrovirology, 21(1), 3. 

Cong, W., Meng, Q.-F., Blaga, R., Villena, I., Zhu, X.-Q., & Qian, A.-D. (2016). Toxoplasma gondii, Dirofilaria immitis, feline immunodeficiency virus (FIV), and feline leukemia virus (FeLV) infections in stray and pet cats (Felis catus) in northwest China: co-infections and risk factors. Parasitology Research, 115(1), 217-223. 

Coyne, M. J., Reeves, N. C. P., & Rosen, D. K. (1997). Estimated prevalence of injection-site sarcomas in cats during 1992. Journal of the American Veterinary Medical Association, 210(2), 249-251. 

Crawford, H. M., Calver, M. C., & Fleming, P. A. (2019). A case of letting the cat out of the bag—Why Trap-Neuter-Return is not an ethical solution for stray cat (Felis catus) management. Animals, 9(4), 171. 

Cronin, K., Page, R. L., Spodnick, G., Dodge, R., Hardie, E. N., Price, G. S.,…Thrall, D. E. (1998). Radiation therapy and surgery for fibrosarcoma in 33 cats. Veterinary Radiology & Ultrasound, 39(1), 51-56. 

Dall’Ara, P., Lauzi, S., Turin, L., Servida, F., Barbieri, L., Zambarbieri, J.,…Mirabile, A. (2023). Prevalence of serum antibody titers against core vaccine antigens in Italian cats. Life, 13(12), 2249. 

Daly, M. K., Saba, C. F., Crochik, S. S., Howerth, E. W., Kosarek, C. E., Cornell, K. K.,…Northrup, N. C. (2008). Fibrosarcoma adjacent to the site of microchip implantation in a cat. Journal of feline medicine and surgery, 10(2), 202-205. 

Danner, R. M., Goltz, D. M., Hess, S. C., & Banko, P. C. (2007). Evidence of feline immunodeficiency virus, feline leukemia virus, and Toxoplasma gondii in feral cats on Mauna Kea, Hawaii. The Journal of Wildlife Diseases, 43(2), 315-318. 

Day, M. J. (2006). Vaccine side effects: fact and fiction. Veterinary microbiology, 117(1), 51-58. 

Day, M. J., Schoon, H. A., Magnol, J. P., Saik, J., Devauchelle, P., Truyen, U.,…Poulet, H. (2007). A kinetic study of histopathological changes in the subcutis of cats injected with non-adjuvanted and adjuvanted multi-component vaccines. Vaccine, 25(20), 4073-4084. 

de Almeida, P. M., & Belas, A. (2025). Prevalence of FeLV and viral subtypes in feral cats. Revista Lusófona de Ciência e Medicina Veterinária, 18, 10-10. 

de Castro, F. L., Junqueira, D. M., de Medeiros, R. M., da Silva, T. R., Costenaro, J. G., Knak, M. B.,…Franco, A. C. (2014). Analysis of single-nucleotide polymorphisms in the APOBEC3H gene of domestic cats (Felis catus) and their association with the susceptibility to feline immunodeficiency virus and feline leukemia virus infections. Infection, Genetics and Evolution, 27, 389-394. https://doi.org/https://doi.org/10.1016/j.meegid.2014.08.024

de Mello, L. S., Ribeiro, P. R., de Almeida, B. A., Bandinelli, M. B., Sonne, L., Driemeier, D., & Pavarini, S. P. (2023). Diseases associated with feline leukemia virus and feline immunodeficiency virus infection: A retrospective study of 1470 necropsied cats (2010–2020). Comparative immunology, microbiology and infectious diseases, 95, 101963. https://doi.org/10.1016/j.cimid.2023.101963

Decreet over dierenwelzijn. (2024, 17 mei). Vlaamse Codex Dierenwelzijn van 17 mei 2024. In. Belgisch Staatsblad.

Diesel, L. P., de Mello, L. S., de Oliveira Santana, W., Ikuta, N., Fonseca, A. S. K., Kipper, D.,…Lunge, V. R. (2024). Epidemiological insights into feline leukemia virus infections in an urban cat (Felis catus) population from Brazil. Animals, 14(7), 1051. 

Dorny, P., Speybroeck, N., Verstraete, S., Baeke, M., De Becker, A., Berkvens, D., & Vercruysse, J. (2002). Serological survey Toxoplasma gondii of a on feline immunodeficiency virus and feine leukaemia virus in urban stray cats in Belgium. Veterinary Record, 151(21), 626-629. 

Duarte, A., Castro, I., da Fonseca, I. M. P., Almeida, V., de Carvalho, L. M. M., Meireles, J.,…Vaz, Y. (2010). Survey of infectious and parasitic diseases in stray cats at the Lisbon Metropolitan Area, Portugal. Journal of feline medicine and surgery, 12(6), 441-446. 

Duarte, A., Fernandes, M., Santos, N., & Tavares, L. (2012). Virological Survey in free-ranging wildcats (Felis silvestris) and feral domestic cats in Portugal. Veterinary Microbiology, 158(3-4), 400-404. 

Dubey, J. P., Lappin, M. R., Kwok, O. C. H., Mofya, S., Chikweto, A., Baffa, A.,…Sharma, R. N. (2009). Seroprevalence of Toxoplasma gondii and concurrent Bartonella spp., feline immunodeficiency virus, and feline leukemia virus infections in cats from Grenada, West Indies. The Journal of parasitology, 95(5), 1129-1133. 

Duijvestijn, M. B. H. M., Schuurman, N. N. M. P., Vernooij, J. C. M., van Leeuwen, M. A. J. M., Bosch, B.-J., van den Brand, J. M. A.,…Verhagen, J. H. (2023). Serological survey of retrovirus and coronavirus infections, including SARS-CoV-2, in rural stray cats in The Netherlands, 2020–2022. Viruses, 15(7), 1531. 

Dunham, S. P., & Graham, E. (2008). Retroviral infections of small animals. Veterinary Clinics of North America: Small Animal Practice, 38(4), 879-901. 

Egberink, H., Frymus, T., Hartmann, K., Möstl, K., Addie, D. D., Belák, S.,…Hosie, M. J. (2022). Vaccination and Antibody Testing in Cats. Viruses, 14(8), 1602. 

Englert, T., Lutz, H., Sauter-Louis, C., & Hartmann, K. (2012). Survey of the feline leukemia virus infection status of cats in Southern Germany. Journal of Feline Medicine and Surgery, 14(6), 392-398. https://doi.org/10.1177/1098612X12440531

Erbeck, K., Gagne, R. B., Kraberger, S., Chiu, E. S., Roelke-Parker, M., & VandeWoude, S. (2021). Feline leukemia virus (FeLV) endogenous and exogenous recombination events result in multiple FeLV-B subtypes during natural infection. Journal of virology, 95(18), 10-1128. 

Eto, N., Yazaki-Takayama, N., Takayama, Y., Yoshino-Nakamura, T., & Kobayashi, Y. (2003). Immuno-chromatographic assay for diagnosis of feline leukemia virus infection. Cytotechnology, 43(1), 65-72. 

European Advisory Board on Cat Diseases. (2009). Guideline for Feline Leukeamia Virus Infection. Retrieved 16 januari 2026 from https://www.abcdcatsvets.org/guideline-for-feline-leukaemia-virus-infection/

Falardeau, J. (2019). Anisocoria. International ophthalmology clinics, 59(3), 125-139. 

Ferreira, G. A., Machado, J. C., Nakano-Oliveira, E., Andriolo, A., & Genaro, G. (2020). The effect of castration on home range size and activity patterns of domestic cats living in a natural area in a protected area on a Brazilian island. Applied Animal Behaviour Science, 230, 105049. 

Finkler, H., Gunther, I., & Terkel, J. (2011). Behavioral differences between urban feeding groups of neutered and sexually intact free-roaming cats following a trap-neuter-return procedure. Journal of the American Veterinary Medical Association, 238(9), 1141-1149. 

Foreman-Worsley, R., Finka, L. R., Ward, S. J., & Farnworth, M. J. (2021). Indoors or outdoors? An international exploration of owner demographics and decision making associated with lifestyle of pet cats. Animals, 11(2), 253. 

Fuchs, A., Binzel, L., & Lonsdorfer, M. (1994). Epidemiology of FeLV and FIV infection in the Federal Republic of Germany. Tierarztliche Praxis, 22(3), 273-277. 

Fusco, G., Marati, L., Pugliese, A., Levante, M., Ferrara, G., De Carlo, E.,…Montagnaro, S. (2023). Prevalence of feline leukemia virus and feline immunodeficiency virus in cats from southern Italy: A 10-year cross-sectional study. Frontiers in Veterinary Science, 10, 1260081. 

Ganten, D., & Ruckpaul, K. (2006). Encyclopedic reference of genomics and proteomics in molecular medicine. Springer. 

Garigliany, M., Jolly, S., Dive, M., Bayrou, C., Berthemin, S., Robin, P.,…Cassart, D. (2016). Risk factors and effect of selective removal on retroviral infections prevalence in Belgian stray cats. Veterinary Record, 178(2), 45-45. 

Gates, M. C., Vigeant, S., & Dale, A. (2017). Prevalence and risk factors for cats testing positive for feline immunodeficiency virus and feline leukaemia virus infection in cats entering an animal shelter in New Zealand. New Zealand veterinary journal, 65(6), 285-291. 

Giselbrecht, J., Jähne, S., Bergmann, M., Meli, M. L., Pineroli, B., Boenzli, E.,…Layachi, N. (2023). Prevalence of different courses of feline leukaemia virus infection in four European countries. Viruses, 15(8), 1718. 

Gleich, S. E., Krieger, S., & Hartmann, K. (2009). Prevalence of feline immunodeficiency virus and feline leukaemia virus among client-owned cats and risk factors for infection in Germany. Journal of Feline Medicine & Surgery, 11(12), 985-992. 

Gobar, G. M., & Kass, P. H. (2002). World Wide Web-based survey of vaccination practices, postvaccinal reactions, and vaccine site-associated sarcomas in cats. Journal of the American Veterinary Medical Association, 220(10), 1477-1482. 

Goldkamp, C. E., Levy, J. K., Edinboro, C. H., & Lachtara, J. L. (2008). Seroprevalences of feline leukemia virus and feline immunodeficiency virus in cats with abscesses or bite wounds and rate of veterinarian compliance with current guidelines for retrovirus testing. Journal of the American Veterinary Medical Association, 232(8), 1152-1158. 

Gomes-Keller, M. A., Gönczi, E., Grenacher, B., Tandon, R., Hofman-Lehmann, R., & Lutz, H. (2009). Fecal shedding of infectious feline leukemia virus and its nucleic acids: A transmission potential. Veterinary Microbiology, 134(3), 208-217. https://doi.org/https://doi.org/10.1016/j.vetmic.2008.08.011

Graham, L. (2012). WHAT’S NEW IN FELV DIAGNOSIS. 

Grosenbaugh, D. A., Frances-Duvert, V., Abedi, S., Feilmeier, B., Ru, H., & Poulet, H. (2017). Efficacy of a nonadjuvanted recombinant FeLV vaccine and two inactivated FeLV vaccines when subject to consistent virulent FeLV challenge conditions. Biologicals, 49, 76-80. 

Grøndahl-Rosado, R. (2009). Rastreio virológico de carnívoros errantes e caracterização genética viral 

Hall, C. M., Bryant, K. A., Haskard, K., Major, T., Bruce, S., & Calver, M. C. (2016). Factors determining the home ranges of pet cats: A meta-analysis. Biological Conservation, 203, 313-320. 

Halls, V., & Bessant, C. (2025). Cat Friendly (End-of-Life) Decision-Making: Euthanasia: how to avoid it and when to use it to support cat welfare. Journal of Shelter Medicine and Community Animal Health, 4(1). 

Hart, B. L., & Barrett, R. E. (1973). Effects of castration on fighting, roaming, and urine spraying in adult male cats. Journal of the American Veterinary Medical Association, 163(3), 290-292. 

Hart, B. L., & Hart, L. A. (2013). Your ideal cat: insights into breed and gender differences in cat behavior. Purdue University Press. 

Hartmann, K. (2012). Clinical aspects of feline retroviruses: a review. Viruses, 4(11), 2684-2710. https://doi.org/10.3390/v4112684

Hartmann, K. (2015). Efficacy of antiviral chemotherapy for retrovirus-infected cats: What does the current literature tell us? Journal of Feline Medicine and Surgery, 17(11), 925-939. 

Hartmann, K., Day, M. J., Thiry, E., Lloret, A., Frymus, T., Addie, D.,…Horzinek, M. C. (2015). Feline injection-site sarcoma: ABCD guidelines on prevention and management. Journal of feline medicine and surgery, 17(7), 606-613. 

Hartmann, K., Egberink, H., Möstl, K., Addie, D. D., Belák, S., Boucraut-Baralon, C.,…Marsilio, F. (2023). Feline injection-site sarcoma and other adverse reactions to vaccination in cats. Viruses, 15(8), 1708. 

Hartmann, K., & Hofmann-Lehmann, R. (2020). What’s new in feline leukemia virus infection. Veterinary Clinics: Small Animal Practice, 50(5), 1013-1036. 

Helfer-Hungerbuehler, A. K., Spiri, A. M., Riond, B., Grest, P., Boretti, F. S., & Hofmann-Lehmann, R. (2015). No benefit of therapeutic vaccination in clinically healthy cats persistently infected with feline leukemia virus. Vaccine, 33(13), 1578-1585. 

Hellard, E., Fouchet, D., Santin-Janin, H., Tarin, B., Badol, V., Coupier, C.,…Pontier, D. (2011). When cats’ ways of life interact with their viruses: A study in 15 natural populations of owned and unowned cats (Felis silvestris catus). Preventive veterinary medicine, 101(3-4), 250-264. 

Hendrick, M. J., Goldschmidt, M. H., Shofer, F. S., Wang, Y.-Y., & Somlyo, A. P. (1992). Postvaccinal sarcomas in the cat: epidemiology and electron probe microanalytical identification of aluminum. Cancer Research, 52(19), 5391-5394. 

Hendrick, M. J., Shofer, F. S., Goldschmidt, M. H., Haviland, J. C., Schelling, S. H., Engler, S. J., & Gliatto, J. M. (1994). Comparison of fibrosarcomas that developed at vaccination sites and at nonvaccination sites in cats: 239 cases (1991–1992). Journal of the American Veterinary Medical Association, 205(10), 1425-1429. 

Hendricks, C. G., Levy, J. K., Tucker, S. J., Olmstead, S. M., Crawford, P. C., Dubovi, E. J., & Hanlon, C. A. (2014). Tail vaccination in cats: a pilot study. Journal of Feline Medicine and Surgery, 16(4), 275-280. 

Hershey, A. E., Sorenmo, K. U., Hendrick, M. J., Shofer, F. S., & Vail, D. M. (2000). Prognosis for presumed feline vaccine-associated sarcoma after excision: 61 cases (1986–1996). Journal of the American Veterinary Medical Association, 216(1), 58-61. 

Hess, R. A., Park, C. J., Soto, S., Reinacher, L., Oh, J.-E., Bunnell, M., & Ko, C. J. (2024). Male animal sterilization: history, current practices, and potential methods for replacing castration. Frontiers in Veterinary Science, 11, 1409386. 

Hofmann-Lehmann, R., Cattori, V., Tandon, R., Boretti, F. S., Meli, M. L., Riond, B., & Lutz, H. (2008). How molecular methods change our views of FeLV infection and vaccination. Veterinary immunology and immunopathology, 123(1-2), 119-123. 

Hofmann-Lehmann, R., Cattori, V., Tandon, R., Boretti, F. S., Meli, M. L., Riond, B.,…Lutz, H. (2007). Vaccination against the feline leukaemia virus: outcome and response categories and long-term follow-up. Vaccine, 25(30), 5531-5539. 

Hofmann-Lehmann, R., & Hartmann, K. (2020). Feline leukaemia virus infection: A practical approach to diagnosis. Journal of Feline Medicine and Surgery, 22(9), 831-846. https://doi.org/10.1177/1098612X20941785

Hofmann-Lehmann, R., & Hartmann, K. (2021). FELINE LEUKAEMIA VIRUS INFECTION – ABCD recommendations and review of the literature. Retrieved 21 december 2025 from https://www.abcdcatsvets.org/guideline-for-feline-leukaemia-virus-infection/

Hofmann-Lehmann, R., Holznagel, E., Aubert, A., Ossent, P., Reinacher, M., & Lutz, H. (1995). Recombinant FeLV vaccine: long-term protection and effect on course and outcome of FIV infection. Veterinary Immunology and Immunopathology, 46(1-2), 127-137. 

Hofmann-Lehmann, R., Tandon, R., Boretti, F. S., Meli, M. L., Willi, B., Cattori, V.,…Flynn, J. N. (2006). Reassessment of feline leukaemia virus (FeLV) vaccines with novel sensitive molecular assays. Vaccine, 24(8), 1087-1094. 

Hoover, E. A., & Mullins, J. I. (1991). Feline leukemia virus infection and diseases. Journal of the American Veterinary Medical Association, 199(10), 1287-1297. 

Hoover, E. A., Mullins, J. I., Chu, H.-J., & Wasmoen, T. L. (1996). Efficacy of an inactivated feline leukemia virus vaccine. AIDS research and human retroviruses, 12(5), 379-383. 

Hoover, E. A., Olsen, R. G., Hardy Jr, W. D., Schaller, J. P., & Mathes, L. E. (1976). Feline leukemia virus infection: age-related variation in response of cats to experimental infection. Journal of the National Cancer Institute, 57(2), 365-369. 

Hoover, E. A., Perigo, N. A., Quackenbush, S. L., Mathiason-DuBard, C. K., Overbaugh, J. M., Kloetzer, W. S.,…Mullins, J. I. (1991). Protection against feline leukemia virus infection by use of an inactivated virus vaccine. Journal of the American Veterinary Medical Association, 199(10), 1392-1401. 

Hosie, M. J., Addie, D., Belák, S., Boucraut-Baralon, C., Egberink, H., Frymus, T.,…Lutz, H. (2009). Feline immunodeficiency. ABCD guidelines on prevention and management. Journal of Feline Medicine & Surgery, 11(7), 575-584. 

Hosie, M. J., Robertson, C., & Jarrett, O. (1989). Prevalence of feline leukaemia virus and antibodies to feline immunodeficiency virus in cats in the United Kingdom. The Veterinary Record, 125(11), 293-297. 

Houser, B., & Vitale, K. R. (2022). Increasing shelter cat welfare through enrichment: A review. Applied Animal Behaviour Science, 248, 105585. 

Huss, A. (2014). Adverse reactions to vaccines in cats. In: SLU, Dept. of Animal Environment and Health (until 231231).

Hwang, J., Gottdenker, N. L., Oh, D.-H., Nam, H.-W., Lee, H., & Chun, M.-S. (2018). Disentangling the link between supplemental feeding, population density, and the prevalence of pathogens in urban stray cats. PeerJ, 6, e4988. 

International Cat Care. (z.d.). Cat Friendly decision-making: FeLV infection and testing in unowned cats. In.

Janssen, J. (2015). Leukemie. In Het oncologie formularium: Een praktische leidraad (pp. 307-324). Springer. 

Jarrett, W., Jarrett, O., MacKey, L., Laird, H., Hood, C., & Hay, D. (1975). Vaccination against feline leukaemia virus using a cell membrane antigen system. International Journal of Cancer, 16(1), 134-141. 

Jarrett, W. F. H., Crawford, E. M., Martin, W. B., & Davie, F. (1964). A virus-like particle associated with leukaemia (lymphosarcoma). 

Juvet, F., Brennan, S., & Mooney, C. T. (2011). Assessment of feline blood for transfusion purposes in the Dublin area of Ireland. Veterinary Record, 168(13), 352-352. 

Kass, P. H., Barnes, W. G., Spangler, W. L., Chomel, B. B., & Culbertson, M. R. (1993). Epidemiologic evidence for a causal relation between vaccination and fibrosarcoma tumorigenesis in cats. Journal of the American Veterinary Medical Association, 203(3), 396-405. 

Kass, P. H., Spangler, W. L., Hendrick, M. J., McGill, L. D., Esplin, D. G., Lester, S.,…Peters, E. M. (2003). Multicenter case-control study of risk factors associated with development of vaccine-associated sarcomas in cats. Journal of the American Veterinary Medical Association, 223(9), 1283-1292. 

Kaulitz, D., Fiebig, U., Eschricht, M., Wurzbacher, C., Kurth, R., & Denner, J. (2011). Generation of neutralising antibodies against porcine endogenous retroviruses (PERVs). Virology, 411(1), 78-86. 

Kawasaki, J., & Nishigaki, K. (2018). Tracking the continuous evolutionary processes of an endogenous retrovirus of the domestic cat: ERV-DC. Viruses, 10(4), 179. 

Kent, M. S., Karchemskiy, S., Culp, W. T. N., Lejeune, A. T., Pesavento, P. A., Toedebusch, C.,…Rebhun, R. (2022). Longevity and mortality in cats: A single institution necropsy study of 3108 cases (1989–2019). PLOS ONE, 17(12), e0278199. https://doi.org/10.1371/journal.pone.0278199

Kessler, M. R., & Turner, D. C. (1999). Effects of Density and Cage Size on Stress in Domestic Cats (Felis Sil Vestris Catus) Housed in Animal Shelters and Boarding Catteries. Animal Welfare, 8(3), 259-267. 

Khalife, S., & Kassaa, I. A. L. (2023). Occurrence and risk factors of feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV) in cats of Lebanon. Comparative immunology, microbiology and infectious diseases, 93, 101931. 

Kliczkowska, K., Jankowska, U., Jagielski, D., Czopowicz, M., & Sapierzynski, R. (2015). Epidemiological and morphological analysis of feline injection site sarcomas. Polish journal of veterinary sciences, 18(2). 

Knol, B. W., & Egberink‐Alink, S. T. (1989). Treatment of problem behaviour in dogs and cats by castration and progestagen administration: A review. Veterinary Quarterly, 11(2), 102-107. 

Knotek, Z., Svoboda, M., Toman, M., & Raška, V. (1999). Epidemiology of feline leukaemia and feline immunodeficiency virus infections in the Czech Republic. Journal of Veterinary Medicine, Series B, 46(10), 665-671. 

Kokkinaki, K. G., Saridomichelakis, M. N., Leontides, L., Mylonakis, M. E., Konstantinidis, A. O., Steiner, J. M.,…Xenoulis, P. G. (2021). A prospective epidemiological, clinical, and clinicopathologic study of feline leukemia virus and feline immunodeficiency virus infection in 435 cats from Greece. Comparative immunology, microbiology and infectious diseases, 78, 101687. 

Koninklijk besluit. (2007, 27 april). Koninklijk besluit van 27 april 2007 houdende erkenningsvoorwaarden voor inrichtingen voor dieren en de voorwaarden inzake de verhandeling van dieren. Belgisch Staatsblad

Krecic, M. R., Velineni, S., Meeus, P., Fan, H., & Loenser, M. (2017). Diagnostic performances of two rapid tests for detection of feline leukemia virus antigen in sera of experimentally feline leukemia virus-infected cats. Journal of Feline Medicine and Surgery Open Reports, 4(1), 2055116917748117. 

Kreisler, R. E., Cornell, H. N., & Levy, J. K. (2019). Decrease in population and increase in welfare of community cats in a twenty-three year trap-neuter-return program in Key Largo, FL: The ORCAT program. Frontiers in veterinary science, 6, 7. 

Kry, K., & Casey, R. (2007). The effect of hiding enrichment on stress levels and behaviour of domestic cats (Felis sylvestris catus) in a shelter setting and the implications for adoption potential. Animal Welfare, 16(3), 375-383. 

Lacerda, L. C., Silva, A. N., Freitas, J. S., Cruz, R. D. S., Said, R. A., & Munhoz, A. D. (2017). Feline immunodeficiency virus and feline leukemia virus: frequency and associated factors in cats in northeastern Brazil. Genet Mol Res, 16(2), 1-8. 

Lamon, T. K., Slater, M. R., Moberly, H. K., & Budke, C. M. (2023). Welfare and quality of life assessments for shelter cats: A scoping review. Applied Animal Behaviour Science, 258, 105797. 

Lee, I. T., Levy, J. K., Gorman, S. P., Crawford, P. C., & Slater, M. R. (2002). Prevalence of feline leukemia virus infection and serum antibodies against feline immunodeficiency virus in unowned free-roaming cats. Journal of the American Veterinary Medical Association, 220(5), 620-622. 

Levy, J., Crawford, C., Hartmann, K., Hofmann-Lehmann, R., Little, S., Sundahl, E., & Thayer, V. (2008). 2008 American Association of Feline Practitioners' feline retrovirus management guidelines. J Feline Med Surg, 10(3), 300-316. https://doi.org/10.1016/j.jfms.2008.03.002

Levy, J. K., & Crawford, P. C. (2004). Humane strategies for controlling feral cat populations. Journal of the American Veterinary Medical Association, 225(9), 1354-1360. 

Levy, J. K., Crawford, P. C., & Slater, M. R. (2004). Effect of vaccination against feline immunodeficiency virus on results of serologic testing in cats. Journal of the American Veterinary Medical Association, 225(10), 1558-1561. 

Levy, J. K., Gale, D. W., & Gale, L. A. (2003). Evaluation of the effect of a long-term trap-neuter-return and adoption program on a free-roaming cat population. Journal of the American Veterinary Medical Association, 222(1), 42-46. 

Levy, J. K., Scott, H. M., Lachtara, J. L., & Crawford, P. C. (2006). Seroprevalence of feline leukemia virus and feline immunodeficiency virus infection among cats in North America and risk factors for seropositivity. Journal of the American veterinary medical association, 228(3), 371-376. 

Little, S., Levy, J., Hartmann, K., Hofmann-Lehmann, R., Hosie, M., Olah, G., & Denis, K. S. (2020). 2020 AAFP feline retrovirus testing and management guidelines. Journal of feline medicine and surgery, 22(1), 5-30. 

Little, S., Sears, W., Lachtara, J., & Bienzle, D. (2009). Seroprevalence of feline leukemia virus and feline immunodeficiency virus infection among cats in Canada. The Canadian Veterinary Journal, 50(6), 644. 

Little, S. E. (2005). Feline immunodeficiency virus testing in stray, feral, and client-owned cats of Ottawa. The Canadian Veterinary Journal, 46(10), 898. 

Lu, H., Liu, Y., Song, Y., Chen, L., Zhang, L., Li, R.,…Wang, L. (2025). Neutralizing Antibodies vs. Viruses: Interacting Mechanisms and Escape Tactics. Microorganisms, 13(9), 2199. 

Luckman, C., & Gates, M. C. (2017). Epidemiology and clinical outcomes of feline immunodeficiency virus and feline leukaemia virus in client-owned cats in New Zealand. Journal of Feline Medicine and Surgery Open Reports, 3(2), 2055116917729311. https://doi.org/10.1177/2055116917729311

Ludwick, K., & Clymer, J. W. (2019). Comparative meta-analysis of feline leukemia virus and feline immunodeficiency virus seroprevalence correlated with GDP per capita around the globe. Research in Veterinary Science, 125, 89-93. https://doi.org/https://doi.org/10.1016/j.rvsc.2019.05.013

Lutz, H., Addie, D., Belák, S., Boucraut-Baralon, C., Egberink, H., Frymus, T.,…Horzinek, M. C. (2009). Feline leukaemia. ABCD guidelines on prevention and management. Journal of Feline Medicine & Surgery, 11(7), 565-574. https://doi.org/https://doi.org/10.1016/j.jfms.2009.05.005

Lutz, H., & Jarrett, O. (1987). Detection of feline leukemia virus infection in saliva. Journal of Clinical Microbiology, 25(5), 827-831. 

Lutz, H., Lehmann, R., Winkler, G., Kottwitz, B., Dittmer, A., Wolfensberger, C., & Arnold, P. (1990). Feline immunodeficiency virus in Switzerland: clinical aspects and epidemiology in comparison with feline leukemia virus and coronaviruses. Schweizer Archiv fur Tierheilkunde, 132(5), 217-225. 

Lutz, H., Pedersen, N. C., & Theilen, G. H. (1983). Course of feline leukemia virus infection and its detection by enzyme-linked immunosorbent assay and monoclonal antibodies. American journal of veterinary research, 44(11), 2054-2059. 

Luzardo, O. P., Vara-Rascón, M., Dufau, A., Infante, E., & Travieso-Aja, M. d. M. (2025). Four years of promising trap–neuter–return (TNR) in Córdoba, Spain: a scalable model for urban feline management. Animals, 15(4), 482. 

Maldonado, R. J., & De Jesus, O. (2020). Hyperesthesia. 

Mattern, M. Y., & McLennan, D. A. (2000). Phylogeny and Speciation of Felids. Cladistics, 16(2), 232-253. https://doi.org/https://doi.org/10.1006/clad.2000.0132

Meli, M. L., Pineroli, B., Geisser, E., & Hofmann-Lehmann, R. (2024). Prospective investigation of feline leukemia virus infection in stray cats subjected to a trap–neuter–return program in Switzerland. Viruses, 16(3), 394. 

Miró, G., Rupérez, C., Checa, R., Gálvez, R., Hernández, L., García, M.,…Montoya, A. (2014). Current status of L. infantum infection in stray cats in the Madrid region (Spain): implications for the recent outbreak of human leishmaniosis? Parasites & Vectors, 7(1), 112. 

Miyazawa, T. (2002). Infections of feline leukemia virus and feline immunodeficiency virus. Front Biosci, 7, d504-d518. 

Montoya, A., García, M., Gálvez, R., Checa, R., Marino, V., Sarquis, J.,…Chicharro, C. (2018). Implications of zoonotic and vector-borne parasites to free-roaming cats in central Spain. Veterinary Parasitology, 251, 125-130. 

Moore, G. E., DeSantis-Kerr, A. C., Guptill, L. F., Glickman, N. W., Lewis, H. B., & Glickman, L. T. (2007). Adverse events after vaccine administration in cats: 2,560 cases (2002–2005). Journal of the American Veterinary Medical Association, 231(1), 94-100. 

Muz, D., Can, H., Karakavuk, M., Döşkaya, M., Özdemir, H. G., Döşkaya, A. D.,…Töz, S. (2021). The molecular and serological investigation of Feline immunodeficiency virus and Feline leukemia virus in stray cats of Western Turkey. Comparative Immunology, Microbiology and Infectious Diseases, 78, 101688. 

Möstl, K., Egberink, H., Addie, D., Frymus, T., Boucraut-Baralon, C., Truyen, U.,…Radford, A. D. (2013). Prevention of infectious diseases in cat shelters: ABCD guidelines. Journal of feline medicine and surgery, 15(7), 546-554. 

Ngo, M. H., Soma, T., Youn, H.-Y., Endo, T., Makundi, I., Kawasaki, J.,…Arnal, M. (2020). Distribution of infectious endogenous retroviruses in mixed-breed and purebred cats. Archives of virology, 165(1). 

Nottingham, C. M., Buckley, H. L., Case, B. S., Glen, A. S., & Stanley, M. C. (2022). Factors affecting home range size of feral cats. New Zealand Journal of Ecology, 46(2), 1-10. 

O'Neil, L. L., Burkhard, M. J., Diehl, L. J., & Hoover, E. A. (1995). Vertical transmission of feline immunodeficiency virus. AIDS research and human retroviruses, 11(1), 171-182. 

Ortega, C., Valencia, A. C., Duque-Valencia, J., & Ruiz-Saenz, J. (2020). Prevalence and genomic diversity of feline leukemia virus in privately owned and shelter cats in Aburrá Valley, Colombia. Viruses, 12(4), 464. 

Oğuzoğlu, T., Muz, D., Timurkan, M., Maral, N., & Gurcan, I. S. (2013). Prevalences of feline coronavirus (FCoV), feline leukaemia virus (FeLV), feline immunodeficiency virus (FIV) and feline parvovirus (FPV) among domestic cats in Ankara, Turkey. Revue Méd Vét, 164(11), 511-516. 

Pacitti, A. M., Jarrett, O., & Hay, D. (1986). Transmission of feline leukaemia virus in the milk of a non-viraemic cat. The veterinary record, 118(14), 381-384. 

Parab, S., & Bhalerao, S. (2010). Choosing statistical test. International journal of Ayurveda research, 1(3), 187. 

Pedersen, N. C., & Barlough, J. E. (1991). Clinical overview of feline immunodeficiency virus. Journal of the American Veterinary Medical Association, 199(10), 1298-1305. 

Polani, S., Roca, A. L., Rosensteel, B. B., Kolokotronis, S.-O., & Bar-Gal, G. K. (2010). Evolutionary dynamics of endogenous feline leukemia virus proliferation among species of the domestic cat lineage. Virology, 405(2), 397-407. 

Polis, I. (2019). Prevalentiestudie naar feliene immunodefiëntievirus en feliene leukosevirus bij straatkatten in Gent. Vlaams Diergeneeskundig Tijdschrift. 

Porcellato, I., Menchetti, L., Brachelente, C., Sforna, M., Reginato, A., Lepri, E., & Mechelli, L. (2017). Feline injection-site sarcoma: matrix remodeling and prognosis. Veterinary pathology, 54(2), 204-211. 

Pramono, D., Muto, Y., Shimazu, Y., Deshapriya, R. M. C., Makundi, I., Arnal, M.,…Nishigaki, K. (2024). Endogenous retrovirus ERV-DC8 highly integrated in domestic cat populations is a replication-competent provirus. Biochemical and Biophysical Research Communications, 738, 150521. 

Prough, R. A., Clark, B. J., & Klinge, C. M. (2016). Novel mechanisms for DHEA action. Journal of molecular endocrinology, 56(3), R139-R155. 

Puga-Torres, B., Navarrete, H., & de la Torre, D. (2025). Retrospective Analysis of Feline Leukemia Virus (FeLV) Frequency in Domestic Cats in Quito, Ecuador (2021–2024). Animals, 15(10), 1469. 

Ravicini, S., Pastor, J., Hawley, J., Brewer, M., Castro-López, J., Beall, M., & Lappin, M. R. (2016). Prevalence of selected infectious disease agents in stray cats in Catalonia, Spain. Journal of Feline Medicine and Surgery Open Reports, 2(1), 2055116916634109. 

Reinacher, M. (1989). Diseases associated with spontaneous feline leukemia virus (FeLV) infection in cats. Veterinary Immunology and Immunopathology, 21(1), 85-95. 

Rojko, J. L., Hoover, E. A., Mathes, L. E., Olsen, R. G., & Schaller, J. P. (1979). Pathogenesis of Experimental Feline Leukemia Virus Infection2. JNCI: Journal of the National Cancer Institute, 63(3), 759-768. https://doi.org/10.1093/jnci/63.3.759

Rosenblatt, J. S., & Aronson, L. R. (1958). The decline of sexual behavior in male cats after castration with special reference to the role of prior sexual experience. Behaviour, 12(4), 285-338. 

Sanjuán, R., & Domingo-Calap, P. (2016). Mechanisms of viral mutation. Cellular and molecular life sciences, 73(23), 4433-4448. 

Schmeltzer, L. E. (2012). Feline leukemia virus diseases. Nursing the Feline Patient, 189-194. 

Shelton, G. H., & Linenberger, M. L. (1995). Hematologic abnormalities associated with retroviral infections in the cat. In (4 ed., Vol. 10, pp. 220-233).

Sivagurunathan, A., Atwa, A. M., & Lobetti, R. (2018). Prevalence of feline immunodeficiency virus and feline leukaemia virus infection in Malaysia: a retrospective study. Journal of Feline Medicine and Surgery Open Reports, 4(1), 2055116917752587. 

Spada, E., Canzi, I., Baggiani, L., Perego, R., Vitale, F., Migliazzo, A., & Proverbio, D. (2016). Prevalence of Leishmania infantum and co-infections in stray cats in northern Italy. Comparative immunology, microbiology and infectious diseases, 45, 53-58. 

Spada, E., Proverbio, D., Pepa, A. d., Perego, R., Baggiani, L., DeGiorgi, G. B.,…Cremonesi, F. (2012). Seroprevalence of feline immunodeficiency virus, feline leukaemia virus and Toxoplasma gondii in stray cat colonies in northern Italy and correlation with clinical and laboratory data. Journal of feline medicine and surgery, 14(6), 369-377. 

Squires, R. A. (2018). Vaccines in shelters and group settings. Veterinary Clinics: Small Animal Practice, 48(2), 291-300. 

Squires, R. A., Crawford, C., Marcondes, M., & Whitley, N. (2024). 2024 guidelines for the vaccination of dogs and cats–compiled by the Vaccination Guidelines Group (VGG) of the World Small Animal Veterinary Association (WSAVA). Journal of small animal practice, 65(5), 277-316. 

Srivastav, A., Kass, P. H., McGill, L. D., Farver, T. B., & Kent, M. S. (2012). Comparative vaccine-specific and other injectable-specific risks of injection-site sarcomas in cats. Journal of the American Veterinary Medical Association, 241(5), 595-602. 

Starr, R. M. (1993). Reaction rate in cats vaccinated with a new controlled-titer feline panleukopenia-rhinotracheitis-calicivirus-Chlamydia psittaci vaccine. The Cornell Veterinarian, 83(4), 311-323. 

Stavisky, J., Dean, R. S., & Molloy, M. H. (2017). Prevalence of and risk factors for FIV and FeLV infection in two shelters in the United Kingdom (2011–2012). Veterinary Record, 181(17), 451-451. 

Stone, A. E. S., Brummet, G. O., Carozza, E. M., Kass, P. H., Petersen, E. P., Sykes, J., & Westman, M. E. (2020). 2020 AAHA/AAFP feline vaccination guidelines. Journal of Feline Medicine and Surgery, 22(9), 813-830. 

Studer, N., Lutz, H., Saegerman, C., Gönczi, E., Meli, M. L., Boo, G.,…Hofmann-Lehmann, R. (2019). Pan-European Study on the Prevalence of the Feline Leukaemia Virus Infection – Reported by the European Advisory Board on Cat Diseases (ABCD Europe). Viruses, 11(11), 993. https://doi.org/10.3390/v11110993

Sukura, A., Salminen, T., & Lindberg, L. A. (1992). A survey of FIV antibodies and FeLV antigens in free-roaming cats in the capital area of Finland. Acta Veterinaria Scandinavica, 33(1), 9-14. 

Suwannachote, T., Prasitsuwan, W., Sumalai, T., & Ruenphet, S. (2025). A Comparison of Diagnostic Methods for Feline Leukemia Virus and Feline Immunodeficiency Virus: Immunochromatographic Assay and RNases Hybridization-Assisted Amplification Test Kit Compared to Reverse Transcription Quantitative Polymerase Chain Reaction. Animals, 15(10), 1484. 

Swango, L. J. (1991). Evaluation of feline leukemia virus diagnostic tests available for in-office use by veterinarians. Journal of the American Veterinary Medical Association, 199(10), 1386-1389. 

Sykes, J. E., & Hartmann, K. (2013). Feline leukemia virus infection. Canine and feline infectious diseases, 224. 

Takita, M., & Kikusui, T. (2016). Early weaning influences short-term synaptic plasticity in the medial prefrontal–anterior basolateral amygdala pathway. Neuroscience research, 103, 48-53. https://doi.org/10.1016/j.neures.2015.08.003

Tejerizo, G., Doménech, A., Illera, J. C., Silván, G., & Gómez-Lucía, E. (2012). Altered plasma concentrations of sex hormones in cats infected by feline immunodeficiency virus or feline leukemia virus. Domestic animal endocrinology, 42(2), 113-120. 

Tenny, S., & Hoffman, M. R. (2017). Prevalence. 

Thiry, E., Addie, D., Belák, S., Boucraut-Baralon, C., Egberink, H., Frymus, T.,…Lloret, A. (2009). Feline herpesvirus infection. ABCD guidelines on prevention and management. Journal of Feline Medicine & Surgery, 11(7), 547-555. 

Torres, A. N., Mathiason, C. K., & Hoover, E. A. (2005). Re-examination of feline leukemia virus: host relationships using real-time PCR. Virology, 332(1), 272-283. 

Truyen, U., Addie, D., Belák, S., Boucraut-Baralon, C., Egberink, H., Frymus, T.,…Lloret, A. (2009). Feline panleukopenia. ABCD guidelines on prevention and management. Journal of Feline Medicine & Surgery, 11(7), 538-546. 

Ueland, K., & Lutz, H. (1992). Prevalence of feline leukemia virus and antibodies to feline immunodeficiency virus in cats in Norway. Journal of Veterinary Medicine, Series B, 39(1‐10), 53-58. 

Van Der Meer, J. W. M., Netea, M. G., & Kullberg, B. J. (1999). Cytokinen en immunotherapie bij infectieziekten. 

Vendramini, T. H. A., Amaral, A. R., Pedrinelli, V., Zafalon, R. V. A., Rodrigues, R. B. A., & Brunetto, M. A. (2020). Neutering in dogs and cats: current scientific evidence and importance of adequate nutritional management. Nutrition research reviews, 33(1), 134-144.

Verburg, M. M., & Bessems, J. (2025). Synovial osteochondromatosis of the sternoclavicular joint in early adolescence. BMJ Case Reports CP, 18(12), e269092. 

Vetcompendium. (z.d.-a). Diergeneesmiddelen - vaccinaties tegen feliene leukemie. Retrieved 21 februari 2026 from https://www.vetcompendium.be/nl/diergeneesmiddelen?f%5B0%5D=doeldier%3A2275&f%5B1%5D=indicatie%3A3041

Vetcompendium. (z.d.-b). Virbegan Omega 10ME. Retrieved 22 februari 2026 from https://www.vetcompendium.be/nl/node/4110

Villanueva-Saz, S., Martínez, M., Giner, J., González, A., Tobajas, A. P., Pérez, M. D.,…Verde, M. (2023). A cross-sectional serosurvey of SARS-CoV-2 and co-infections in stray cats from the second wave to the sixth wave of COVID-19 outbreaks in Spain. Veterinary research communications, 47(2), 615-629. 

Villanueva‐Saz, S., Giner, J., Tobajas, A. P., Pérez, M. D., González‐Ramírez, A. M., Macías‐León, J.,…Hurtado‐Guerrero, R. (2022). Serological evidence of SARS‐CoV‐2 and co‐infections in stray cats in Spain. Transboundary and Emerging Diseases, 69(3), 1056-1064. 

Vinke, C. M., Godijn, L. M., & Van der Leij, W. J. R. (2014). Will a hiding box provide stress reduction for shelter cats? Applied Animal Behaviour Science, 160, 86-93. 

Vlaamse Overheid. (2021). Een diervriendelijk gemeentelijk zwerfkattenbeleid. Een gids voor lokale besturen. Retrieved 15 februari 2026 from https://www.vlaanderen.be/publicaties/een-diervriendelijk-gemeentelijk-zwerfkattenbeleid-een-gids-voor-de-lokale-besturen

Vlaamse Overheid. (z.d.-a). Animal Shelter voor dierenasielen. Retrieved 10 april 2026 from https://www.vlaanderen.be/natuur-milieu-en-klimaat/dieren/huisdieren-en-landbouwhuisdieren/animal-shelter-voor-dierenasielen#subsidie-voor-dierenasielen

Vlaamse overheid. (z.d.). Cijfers dierenwelzijn. Retrieved 8 januari 2026 from https://www.vlaanderen.be/dierenwelzijn/werking-en-beleid/cijfers-dierenwelzijn#asielcijfers

Vlaamse Overheid. (z.d.-b). Erkende dierenasielen. Retrieved 7 december 2025 from https://www.vlaanderen.be/natuur-milieu-en-klimaat/dieren/erkende-dierenasielen

Vlaamse Overheid. (z.d.-c). Identificatie en registratie van katten. Retrieved 22 februari 2026 from https://www.vlaanderen.be/natuur-milieu-en-klimaat/dieren/huisdieren-en-landbouwhuisdieren/identificatie-en-registratie-van-katten

Vlaamse Regering. (2026). Besluit van de Vlaamse Regering tot wijziging van het koninklijk besluit van 27 april 2007 houdende erkenningsvoorwaarden voor inrichtingen voor dieren en de voorwaarden inzake de verhandeling van dieren, wat betreft de indexatie van de retributie, afwijkingen op quarantainenormen in asielen en de vaccinatieplicht voor katten. 

Vobis, M., D’haese, J., Mehlhorn, H., & Mencke, N. (2003). The feline leukemia virus (FeLV) and the cat flea (Ctenocephalides felis). Parasitology research, 90(Suppl 3), S132-S134. 

Vojtkovská, V., Voslářová, E., & Večerek, V. (2020). Methods of assessment of the welfare of shelter cats: a review. Animals, 10(9), 1527. 

Wagner, D., Hurley, K., & Stavisky, J. (2018). Shelter housing for cats: Principles of design for health, welfare and rehoming. Journal of feline medicine and surgery, 20(7), 635-642. 

Weijer, K., UijtdeHaag, F., & Osterhaus, A. (1986). Control of feline leukaemia virus infection by a removal programme. 

Westman, Parr, Y., Martin, C., Wuestner, E., Pan, S., Norris, J. M.,…Hall, E. (2025). Antibody responses to feline leukaemia vaccination: exploring the effect of sex, boosting schedule, site of administration and vaccine type. Journal of Feline Medicine and Surgery, 27(9), 1098612X251353080. 

Westman, M., Norris, J., Malik, R., Hofmann-Lehmann, R., Harvey, A., McLuckie, A.,…Hosie, M. (2019). The Diagnosis of Feline Leukaemia Virus (FeLV) Infection in Owned and Group-Housed Rescue Cats in Australia. Viruses, 11(6), 503. 

Westman, M. E., Coggins, S. J., Van Dorsselaer, M., Norris, J. M., Squires, R. A., Thompson, M., & Malik, R. (2025). Feline leukaemia virus (FeLV) infection in domestic pet cats in Australia and New Zealand: Guidelines for diagnosis, prevention and management. Australian Veterinary Journal, 103(10), 617-635. 

Westman, M. E., Malik, R., Hall, E., Sheehy, P. A., & Norris, J. M. (2017). Comparison of three feline leukaemia virus (FeLV) point-of-care antigen test kits using blood and saliva. Comparative Immunology, Microbiology and Infectious Diseases, 50, 88-96. https://doi.org/https://doi.org/10.1016/j.cimid.2016.11.014

Westman, M. E., Malik, R., & Norris, J. M. (2019). Diagnosing feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV) infection: an update for clinicians. Australian veterinary journal, 97(3), 47-55. https://doi.org/10.1111/avj.12781 

Westman, M. E., Parr, Y., Martin, C., Wuestner, E., Pan, S., Norris, J. M.,…Hall, E. (2025). Antibody responses to feline leukaemia vaccination: exploring the effect of sex, boosting schedule, site of administration and vaccine type. Journal of Feline Medicine and Surgery, 27(9), 1098612X251353080. 

Westman, M. E., Paul, A., Malik, R., McDonagh, P., Ward, M. P., Hall, E., & Norris, J. M. (2016). Seroprevalence of feline immunodeficiency virus and feline leukaemia virus in Australia: risk factors for infection and geographical influences (2011–2013). Journal of Feline Medicine and Surgery Open Reports, 2(1), 2055116916646388. 

Wet. (2018, 30 juli). Wet betreffende de bescherming van natuurlijke personen met betrekking tot de verwerking van persoonsgegevens. In. Belgisch Staatsblad.

Wilcock, B., Wilcock, A., & Bottoms, K. (2012). Feline postvaccinal sarcoma: 20 years later. The Canadian veterinary journal, 53(4), 430. 

Wolf, P. J., Rand, J., Swarbrick, H., Spehar, D. D., & Norris, J. (2019). Reply to Crawford et al.: Why trap-neuter-return (TNR) is an ethical solution for stray cat management. Animals, 9(9), 689. 

Yahiaoui, F., Kardjadj, M., & Ben-Mahdi, M. H. (2024). First seroprevalence study of feline leukemia and feline immunodeficiency infections among cats in Algiers (Algeria) and associated risk factors. Veterinary Sciences, 11(11), 546. 

Úsuga-Monroy, C., Alzate-Pavas, J., Ortiz-González, M. A., Villa, J. M., Loaiza-Escobar, J., Sánchez-Zapata, G. Y., & Gómez-Ruiz, D. A. (2025). Prevalence, Recombination Events, and Risk Factors of FeLV Infection in Domestic Cats from Colombia. Veterinaria Italiana, 61(2). 

Download scriptie (1.25 MB)
Universiteit of Hogeschool
Odisee Hogeschool
Thesis jaar
2026
Promotor(en) en begeleiders
Els Peeters
Thema('s)