Collicular-driven stopping behavior is modulated by the posterior paralaminar nuclei of the thalamus
Universiteit Antwerpen
2020
Genomineerde shortlist Eosprijs
This project examines the contribution of a specific brain region, the posterior paralaminar nuclei of the thalamus (PPnT), to innate stopping behavior in mice. We found that inhibition of the PPnT facilitates habituation to repeated stimulation of NTSR neurons in the superior colliculus. These results have implications for understanding and treating similar circuits involved in human disease, such as in post-traumatic stress disorder.
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